What is a common sequelae of a GABHS infection?

What is a common sequelae of a GABHS infection?

• A. Celiac disease
• B. Appendicitis
• C. Glomerulonephritis
• D. Cholecystitis

Answer: (C)

A common sequela of a Group A beta-hemolytic streptococcal (GABHS) infection is glomerulonephritis. This condition can develop following an infection with GABHS, which typically manifests as strep throat or skin infections such as impetigo. The pathophysiology behind this connection involves the body's immune response to the streptococcal bacteria, leading to the formation of immune complexes. These complexes can deposit in the kidneys, triggering inflammation and damage to the glomeruli, the filtering units of the kidneys. Symptoms of post-streptococcal glomerulonephritis can include hematuria (blood in the urine), proteinuria (excess protein in the urine), elevated blood pressure, and edema. Celiac disease, appendicitis, and cholecystitis are not direct sequelae of GABHS infections. Celiac disease is an autoimmune disorder triggered by gluten, while appendicitis is an inflammation of the appendix and does not have a direct link to streptococcal infections. Cholecystitis involves inflammation of the gallbladder, often due to gallstones, rather than an infection like GABHS.

A common sequela of a Group A beta-hemolytic streptococcal (GABHS) infection is glomerulonephritis. This condition can develop following an infection with GABHS, which typically manifests as strep throat or skin infections such as impetigo.

The pathophysiology behind this connection involves the body's immune response to the streptococcal bacteria, leading to the formation of immune complexes. These complexes can deposit in the kidneys, triggering inflammation and damage to the glomeruli, the filtering units of the kidneys. Symptoms of post-streptococcal glomerulonephritis can include hematuria (blood in the urine), proteinuria (excess protein in the urine), elevated blood pressure, and edema.

Celiac disease, appendicitis, and cholecystitis are not direct sequelae of GABHS infections. Celiac disease is an autoimmune disorder triggered by gluten, while appendicitis is an inflammation of the appendix and does not have a direct link to streptococcal infections. Cholecystitis involves inflammation of the gallbladder, often due to gallstones, rather than an infection like GABHS.